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    psph phosphoserine phosphatase [ Danio rerio (zebrafish) ]

    Gene ID: 606663, updated on 2-Nov-2024

    Summary

    Official Symbol
    psphprovided by ZNC
    Official Full Name
    phosphoserine phosphataseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050809-127
    See related
    Ensembl:ENSDARG00000040314 AllianceGenome:ZFIN:ZDB-GENE-050809-127
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112414
    Summary
    Predicted to enable L-phosphoserine phosphatase activity and magnesium ion binding activity. Predicted to be involved in L-serine biosynthetic process. Predicted to act upstream of or within amino acid biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in PSPH deficiency. Orthologous to human PSPH (phosphoserine phosphatase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See psph in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (413769..419756, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (504296..511869, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene elastin a Neighboring gene uncharacterized LOC137487705 Neighboring gene nipsnap homolog 2 Neighboring gene centrosomal protein 295 Neighboring gene mediator complex subunit 17

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC112414

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables L-phosphoserine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-phosphoserine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in L-serine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within L-serine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within amino acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    phosphoserine phosphatase
    NP_001028271.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033099.1NP_001028271.1  phosphoserine phosphatase

      See identical proteins and their annotated locations for NP_001028271.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100056
      UniProtKB/TrEMBL
      Q498V7
      Related
      ENSDARP00000058992.7, ENSDART00000058993.7
      Conserved Domains (2) summary
      PLN02954
      Location:9224
      PLN02954; phosphoserine phosphatase
      pfam00702
      Location:15186
      Hydrolase; haloacid dehalogenase-like hydrolase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      413769..419756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)