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    DIP-delta Dpr-interacting protein delta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740816, updated on 2-Nov-2024

    Summary

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    Official Symbol
    DIP-deltaprovided by FlyBase
    Official Full Name
    Dpr-interacting protein deltaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085420
    Locus tag
    Dmel_CG34391
    See related
    AllianceGenome:FB:FBgn0085420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    34391; CG15214; CG34391; CG4814; CT15465; CT35147; DIPdelta; Dmel\CG34391
    Old locus tag
    CG15214; CG4814; Dmel_CG15214; Dmel_CG4814
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection. Is expressed in adult head; embryonic/larval crystal cell; optic lobe intrinsic neurons; and procrystal cell. Orthologous to several human genes including LSAMP (limbic system associated membrane protein). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

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    See DIP-delta in Genome Data Viewer
    Location:
    64D1-64D1; 3-14 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5424109..5442399)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5417209..5435499)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45743 Neighboring gene Ionotropic receptor 64a Neighboring gene long non-coding RNA:CR44520 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal Control of Neuronal Remodeling by Cell Adhesion Molecules: Insights From Drosophila. Meltzer H, et al. Front Neurosci, 2022. PMID 35645712, Free PMC Article
    2. Coordination between stochastic and deterministic specification in the Drosophila visual system. Courgeon M, et al. Science, 2019 Oct 18. PMID 31582524, Free PMC Article
    3. Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons. Bornstein B, et al. EMBO J, 2021 Jun 15. PMID 33847376, Free PMC Article
    4. A single cell genomics atlas of the Drosophila larval eye reveals distinct photoreceptor developmental timelines. Bollepogu Raja KK, et al. Nat Commun, 2023 Nov 8. PMID 37938573, Free PMC Article
    5. A double-negative gene regulatory circuit underlies the virgin behavioral state. Garaulet DL, et al. Cell Rep, 2021 Jul 6. PMID 34233178, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transneuronal Dpr12/DIP-delta interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons.
      Title: Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dpr-interacting protein delta
    Names
    CG34391-PB
    CG34391-PD
    CG34391-PE
    DIP-delta-PB
    DIP-delta-PD
    DIP-delta-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5424109..5442399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274512.2 → NP_001261441.1  Dpr-interacting protein delta, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNC7, Q1RKT2
      Conserved Domains (3) summary
      smart00409
      Location:51 → 143
      IG; Immunoglobulin
      cd00096
      Location:145 → 149
      Ig; Ig strand A [structural motif]
      cl11960
      Location:145 → 238
      Ig; Immunoglobulin domain

    2. NM_001104038.4 → NP_001097508.2  Dpr-interacting protein delta, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097508.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNC7, Q1RKT2
      Conserved Domains (3) summary
      smart00409
      Location:51 → 143
      IG; Immunoglobulin
      cd00096
      Location:145 → 149
      Ig; Ig strand A [structural motif]
      cl11960
      Location:145 → 238
      Ig; Immunoglobulin domain

    3. NM_001144414.3 → NP_001137886.1  Dpr-interacting protein delta, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137886.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2QCS9, Q4QQ54, Q4QQ69
      Conserved Domains (2) summary
      cd00096
      Location:9 → 13
      Ig; Ig strand D [structural motif]
      cl11960
      Location:1 → 53
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JNC7 A8JNC7
    Q4QQ69 Q4QQ69

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