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    CG34171 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740474, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG34171provided by FlyBase
    Primary source
    FLYBASE:FBgn0085200
    Locus tag
    Dmel_CG34171
    See related
    AllianceGenome:FB:FBgn0085200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG34171; SPH244
    Summary
    Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG34171 in Genome Data Viewer
    Location:
    36F3-36F3; 2-53 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18378591..18379909)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18378591..18379909)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44489 Neighboring gene Fasciclin 3 Neighboring gene Accessory gland protein 36DE Neighboring gene long non-coding RNA:CR44486 Neighboring gene long non-coding RNA:CR44487

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
    2. Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. Palu RA, et al. PLoS Genet, 2016 Apr. PMID 27058248, Free PMC Article
    3. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    4. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
    5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34171-PB
    CG34171-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18378591..18379909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299112.1 → NP_001286041.1  uncharacterized protein Dmel_CG34171, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286041.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JEK1
      Conserved Domains (1) summary
      cl21584
      Location:38 → 161
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. NM_001103705.3 → NP_001097175.2  uncharacterized protein Dmel_CG34171, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097175.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DZ15
      Conserved Domains (2) summary
      pfam00089
      Location:29 → 260
      Trypsin; Trypsin
      cl21584
      Location:38 → 263
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8DZ15 A8DZ15
    X2JEK1 X2JEK1

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