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    fbxl7 F-box and leucine-rich repeat protein 7 [ Danio rerio (zebrafish) ]

    Gene ID: 569430, updated on 2-Nov-2024

    Summary

    Official Symbol
    fbxl7provided by ZNC
    Official Full Name
    F-box and leucine-rich repeat protein 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061215-122
    See related
    Ensembl:ENSDARG00000062251 AllianceGenome:ZFIN:ZDB-GENE-061215-122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:158339; zgc:158346
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in centrosome and cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL7 (F-box and leucine rich repeat protein 7). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See fbxl7 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (21634128..21734733)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21976066..22076671)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene v-ral simian leukemia viral oncogene homolog Ab (ras related) Neighboring gene zgc:55781 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene chromodomain helicase DNA binding protein 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC158346

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080042.1NP_001073511.1  F-box/LRR-repeat protein 7

      See identical proteins and their annotated locations for NP_001073511.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129207
      UniProtKB/Swiss-Prot
      A1A5X2
      Related
      ENSDARP00000084255.4, ENSDART00000089822.5
      Conserved Domains (3) summary
      cd09293
      Location:295463
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:238271
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:112158
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      21634128..21734733
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)