U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    si:ch211-213a13.9 si:ch211-213a13.9 [ Danio rerio (zebrafish) ]

    Gene ID: 569389, updated on 28-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    si:ch211-213a13.9provided by ZNC
    Official Full Name
    si:ch211-213a13.9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-632
    See related
    Ensembl:ENSDARG00000074546 AllianceGenome:ZFIN:ZDB-GENE-050208-632
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14). [provided by Alliance of Genome Resources, Oct 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See si:ch211-213a13.9 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (9060705..9096173)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (9031030..9066488)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438296 Neighboring gene ribonuclease/angiogenin inhibitor 1 Neighboring gene protein NLRC3-like Neighboring gene ribonuclease inhibitor-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The expanding and function of NLRC3 or NLRC3-like in teleost fish: Recent advances and novel insights. Chang MX, et al. Dev Comp Immunol, 2021 Jan. PMID 32896535

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    NLR family CARD domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      9060705..9096173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469437.2 → XP_021325112.1  NLR family CARD domain-containing protein 3

      UniProtKB/TrEMBL
      A0A8M9P4F8
      Related
      ENSDARP00000119526.2, ENSDART00000133993.3
      Conserved Domains (6) summary
      COG5635
      Location:61 → 709
      COG5635; Predicted NTPase, NACHT family domain [Signal transduction mechanisms]
      sd00033
      Location:1401 → 1428
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:829 → 856
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:261 → 429
      NACHT; NACHT domain
      pfam14484
      Location:181 → 251
      FISNA; Fish-specific NACHT associated domain
      cl26161
      Location:805 → 1086
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials