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    mov10a Mov10 RNA helicase a [ Danio rerio (zebrafish) ]

    Gene ID: 566858, updated on 2-Nov-2024

    Summary

    Official Symbol
    mov10aprovided by ZNC
    Official Full Name
    Mov10 RNA helicase aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091230-8
    See related
    Ensembl:ENSDARG00000015829 AllianceGenome:ZFIN:ZDB-GENE-091230-8
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in P-body. Predicted to be active in P granule and cytosol. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RNA helicase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See mov10a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (48348398..48376245)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (48349645..48377486)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene suppression of tumorigenicity 7 like Neighboring gene capping actin protein of muscle Z-line subunit alpha 1a Neighboring gene uncharacterized LOC137496016 Neighboring gene ras homolog family member Ca

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 5'-3' RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated post-transcriptional gene silencing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in P granule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative helicase mov-10-B.1
    Names
    Moloney leukemia virus 10, homolog, a
    Moloney leukemia virus 10a
    Mov10 RISC complex RNA helicase a
    Mov10, Moloney leukemia virus 10, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      48348398..48376245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002662530.5XP_002662576.2  putative helicase mov-10-B.1

      UniProtKB/TrEMBL
      A0A8M1RLW1, E7FAV9
      Related
      ENSDARP00000064825.5, ENSDART00000064826.7
      Conserved Domains (4) summary
      COG1112
      Location:634963
      DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
      pfam13086
      Location:517704
      AAA_11; AAA domain
      pfam13087
      Location:711934
      AAA_12; AAA domain
      cl21455
      Location:517709
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases