rnf213b ring finger protein 213b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rnf213bprovided by ZNC
Official Full Name: ring finger protein 213bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-110822-1
See related: Ensembl:ENSDARG00000103551 AllianceGenome:ZFIN:ZDB-GENE-110822-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rnf213
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in negative regulation of non-canonical Wnt signaling pathway; sprouting angiogenesis; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleolus. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human RNF213 (ring finger protein 213). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 61

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (35886960..35936332, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (36195346..36242074, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of non-canonical Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in sprouting angiogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase rnf213-beta

Names: E3 ubiquitin-lipopolysaccharide ligase rnf213-beta; RING finger protein 213-B; RING finger protein 213-beta; RING-type E3 ubiquitin transferase rnf213-beta; mysterin-B; mysterin-beta; ring finger protein 213

NP_001340796.2

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.