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    fnbp1b formin binding protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 562049, updated on 28-Oct-2024

    Summary

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    Official Symbol
    fnbp1bprovided by ZNC
    Official Full Name
    formin binding protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091117-6
    See related
    Ensembl:ENSDARG00000101028 AllianceGenome:ZFIN:ZDB-GENE-091117-6
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-225g23.2
    Summary
    Predicted to enable lipid binding activity. Predicted to act upstream of or within endocytosis and signal transduction. Predicted to be located in cell cortex and plasma membrane. [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See fnbp1b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (6212917..6390587)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (6107194..6280599)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene si:dkey-93m18.3 Neighboring gene si:dkey-93m18.4 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene centromere protein T

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. Balciuniene J, et al. BMC Genomics, 2013 Sep 14. PMID 24034702, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    formin-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      6212917..6390587
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068215986.1 → XP_068072087.1  formin-binding protein 1 isoform X26

    2. XM_068215987.1 → XP_068072088.1  formin-binding protein 1 isoform X27

    3. XM_068215979.1 → XP_068072080.1  formin-binding protein 1 isoform X12

    4. XM_068215985.1 → XP_068072086.1  formin-binding protein 1 isoform X25

      Related
      ENSDARP00000145014.1, ENSDART00000184952.1

    5. XM_068215972.1 → XP_068072073.1  formin-binding protein 1 isoform X1

    6. XM_068215974.1 → XP_068072075.1  formin-binding protein 1 isoform X3

    7. XM_068215976.1 → XP_068072077.1  formin-binding protein 1 isoform X5

      Related
      ENSDARP00000144914.1, ENSDART00000184006.1

    8. XM_021468987.2 → XP_021324662.1  formin-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9P3K0
      Conserved Domains (3) summary
      cl00087
      Location:464 → 540
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:621 → 677
      SH3; Src Homology 3 domain superfamily

    9. XM_021468990.2 → XP_021324665.1  formin-binding protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PUD4
      Conserved Domains (3) summary
      cl00087
      Location:459 → 535
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:616 → 672
      SH3; Src Homology 3 domain superfamily

    10. XM_068215980.1 → XP_068072081.1  formin-binding protein 1 isoform X13

    11. XM_068215977.1 → XP_068072078.1  formin-binding protein 1 isoform X7

    12. XM_009295146.4 → XP_009293421.1  formin-binding protein 1 isoform X15

      UniProtKB/TrEMBL
      A0A8M3AWL7
      Conserved Domains (3) summary
      cl00087
      Location:432 → 508
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:589 → 645
      SH3; Src Homology 3 domain superfamily

    13. XM_068215973.1 → XP_068072074.1  formin-binding protein 1 isoform X2

    14. XM_021468992.2 → XP_021324667.1  formin-binding protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8M9P3K2
      Conserved Domains (3) summary
      cl00087
      Location:452 → 528
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:609 → 665
      SH3; Src Homology 3 domain superfamily

    15. XM_068215975.1 → XP_068072076.1  formin-binding protein 1 isoform X4

    16. XM_009295153.4 → XP_009293428.1  formin-binding protein 1 isoform X18

      UniProtKB/TrEMBL
      A0A8M3B4H4
      Conserved Domains (3) summary
      cl00087
      Location:400 → 476
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:557 → 613
      SH3; Src Homology 3 domain superfamily

    17. XM_009295155.4 → XP_009293430.1  formin-binding protein 1 isoform X19

      UniProtKB/TrEMBL
      A0A8M3AWM2
      Conserved Domains (3) summary
      cl00087
      Location:388 → 464
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:545 → 601
      SH3; Src Homology 3 domain superfamily

    18. XM_009295158.4 → XP_009293433.1  formin-binding protein 1 isoform X21

      UniProtKB/TrEMBL
      A0A8M3B4H7
      Conserved Domains (3) summary
      cl00087
      Location:383 → 459
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:540 → 596
      SH3; Src Homology 3 domain superfamily

    19. XM_009295142.4 → XP_009293417.1  formin-binding protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A8M3ALX1
      Conserved Domains (3) summary
      cl00087
      Location:452 → 528
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:608 → 664
      SH3; Src Homology 3 domain superfamily

    20. XM_068215981.1 → XP_068072082.1  formin-binding protein 1 isoform X14

      Related
      ENSDARP00000137643.2, ENSDART00000161647.3

    21. XM_009295151.4 → XP_009293426.1  formin-binding protein 1 isoform X16

      UniProtKB/TrEMBL
      A0A8M3AL85
      Conserved Domains (3) summary
      cl00087
      Location:420 → 496
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:576 → 632
      SH3; Src Homology 3 domain superfamily

    22. XM_068215982.1 → XP_068072083.1  formin-binding protein 1 isoform X17

    23. XM_068215983.1 → XP_068072084.1  formin-binding protein 1 isoform X23

    24. XM_009295157.4 → XP_009293432.1  formin-binding protein 1 isoform X20

      UniProtKB/TrEMBL
      A0A8M3AL88
      Conserved Domains (3) summary
      cl00087
      Location:388 → 464
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:544 → 600
      SH3; Src Homology 3 domain superfamily

    25. XM_009295159.4 → XP_009293434.1  formin-binding protein 1 isoform X22

      UniProtKB/TrEMBL
      A0A8M3ALY0
      Conserved Domains (3) summary
      cl00087
      Location:383 → 459
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
      cl12013
      Location:54 → 300
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl17036
      Location:539 → 595
      SH3; Src Homology 3 domain superfamily

    26. XM_068215984.1 → XP_068072085.1  formin-binding protein 1 isoform X24

    27. XM_068215978.1 → XP_068072079.1  formin-binding protein 1 isoform X9

    28. XM_068215988.1 → XP_068072089.1  formin-binding protein 1 isoform X28

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395078.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      160332..256284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473389.2 → XP_021329064.1  formin-binding protein 1 isoform X31

      UniProtKB/TrEMBL
      A0A8M9PW73
      Conserved Domains (1) summary
      cl12013
      Location:5 → 113
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_021473387.2 → XP_021329062.1  formin-binding protein 1 isoform X29

      UniProtKB/TrEMBL
      A0A8M9PD94
      Conserved Domains (1) summary
      cl12013
      Location:54 → 158
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_021473388.2 → XP_021329063.1  formin-binding protein 1 isoform X30

      UniProtKB/TrEMBL
      A0A8M9PPV6
      Conserved Domains (1) summary
      cl12013
      Location:15 → 119
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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