hist1h2a1 histone cluster 1 H2A family member1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hist1h2a1provided by ZNC
Official Full Name: histone cluster 1 H2A family member1provided by ZNC
Primary source: ZFIN:ZDB-GENE-121214-150
See related: AllianceGenome:ZFIN:ZDB-GENE-121214-150
Gene type: protein coding
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-113a14.16
Summary: Predicted to be a structural constituent of chromatin. Predicted to be involved in defense response to other organism; disruption of plasma membrane integrity in another organism; and heterochromatin formation. Predicted to be located in extracellular space. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to several human genes including H2AC11 (H2A clustered histone 11); H2AC13 (H2A clustered histone 13); and H2AC15 (H2A clustered histone 15). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: not in current annotation release
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Annotation release	Status	Assembly	Chr	Location
106	latest, but not current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (36336823..36337356)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (35787169..35787639)

Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.
Title: Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-positive bacterium	ISS Inferred from Sequence or Structural Similarity more info
involved_in disruption of plasma membrane integrity in another organism	ISS Inferred from Sequence or Structural Similarity more info
involved_in heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in innate immune response	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in extracellular space	ISS Inferred from Sequence or Structural Similarity more info
part_of nucleosome	IBA Inferred from Biological aspect of Ancestor more info
part_of nucleosome	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info