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    hist1h2a5 histone cluster 1 H2A family member 5 [ Danio rerio (zebrafish) ]

    Gene ID: 559220, updated on 17-Aug-2024

    Summary

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    Official Symbol
    hist1h2a5provided by ZNC
    Official Full Name
    histone cluster 1 H2A family member 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131121-77
    See related
    Ensembl:ENSDARG00000114133 AllianceGenome:ZFIN:ZDB-GENE-131121-77
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-261m9.15
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in heterochromatin assembly. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Orthologous to human H2AC21 (H2A clustered histone 21). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (35151778..35152374, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (34646598..34647383, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene si:dkey-261m9.17 Neighboring gene zgc:113984 Neighboring gene zgc:153405 Neighboring gene anoctamin-9-like Neighboring gene anoctamin 9a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel O-GlcNAcylation on Ser(40) of canonical H2A isoforms specific to viviparity. Hirosawa M, et al. Sci Rep, 2016 Sep 12. PMID 27615797, Free PMC Article
    2. Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration. Chen WC, et al. Sci Adv, 2016 Nov. PMID 28138518, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleosomal DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    histone H2A-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      35151778..35152374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163219.4 → XP_005163276.1  histone H2A-like

      UniProtKB/TrEMBL
      A0A8M2BA83, A6QL59, E7EZX1
      Related
      ENSDARP00000104399.2, ENSDART00000114908.3
      Conserved Domains (2) summary
      PTZ00017
      Location:1 → 128
      PTZ00017; histone H2A; Provisional
      cd00074
      Location:6 → 120
      H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
    Nucleotide Protein Strain
    Heading Accession and Version

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