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    abhd6b abhydrolase domain containing 6, acylglycerol lipase b [ Danio rerio (zebrafish) ]

    Gene ID: 558995, updated on 2-Nov-2024

    Summary

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    Official Symbol
    abhd6bprovided by ZNC
    Official Full Name
    abhydrolase domain containing 6, acylglycerol lipase bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070410-104
    See related
    Ensembl:ENSDARG00000070894 AllianceGenome:ZFIN:ZDB-GENE-070410-104
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:162889
    Summary
    Predicted to enable monoacylglycerol lipase activity. Predicted to be involved in acylglycerol catabolic process. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in membrane. Orthologous to human ABHD6 (abhydrolase domain containing 6, acylglycerol lipase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See abhd6b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (19655301..19667827)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (19728958..19741977)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene sarcolemma associated protein b Neighboring gene filamin B, beta (actin binding protein 278) Neighboring gene potassium channel tetramerization domain containing 6b Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates. Kassahn KS, et al. Genome Res, 2009 Aug. PMID 19439512, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC162889

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables monoacylglycerol lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acylglycerol catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of AMPA glutamate receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    monoacylglycerol lipase ABHD6b
    Names
    abhydrolase domain containing 6b
    NP_001315288.1
    XP_009295019.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328359.1 → NP_001315288.1  monoacylglycerol lipase ABHD6b

      Status: VALIDATED

      Source sequence(s)
      CR376797, EH542669, EH563805
      UniProtKB/TrEMBL
      A0A8M1P4P5
      Related
      ENSDARP00000117538.1, ENSDART00000135269.2
      Conserved Domains (2) summary
      COG0596
      Location:56 → 329
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      cl21494
      Location:76 → 173
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      19655301..19667827
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009296744.4 → XP_009295019.1  monoacylglycerol lipase ABHD6b isoform X1

      See identical proteins and their annotated locations for XP_009295019.1

      UniProtKB/TrEMBL
      A0A8M1P4P5
      Conserved Domains (2) summary
      COG0596
      Location:56 → 329
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      cl21494
      Location:76 → 173
      Abhydrolase; alpha/beta hydrolases

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395361.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      186061..197378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001089495.1: Suppressed sequence

      Description
      NM_001089495.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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