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    nom1 nucleolar protein with MIF4G domain 1 [ Danio rerio (zebrafish) ]

    Gene ID: 557585, updated on 28-Oct-2024

    Summary

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    Official Symbol
    nom1provided by ZNC
    Official Full Name
    nucleolar protein with MIF4G domain 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-321
    See related
    Ensembl:ENSDARG00000060027 AllianceGenome:ZFIN:ZDB-GENE-060503-321
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-266o5.1
    Summary
    Predicted to enable RNA binding activity. Acts upstream of or within ribosome biogenesis. Predicted to be active in nucleolus. Is expressed in brain; intestine; liver; and pancreas. Orthologous to human NOM1 (nucleolar protein with MIF4G domain 1). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nom1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (40644872..40657791, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (40373855..40386774, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene ubiquitin protein ligase E3C Neighboring gene motor neuron and pancreas homeobox 1 Neighboring gene limb development membrane protein 1 Neighboring gene ring finger protein 32

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish. Qin W, et al. PLoS One, 2014. PMID 24967912, Free PMC Article
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. a new mechanism involving Nom1 in controlling vertebrate exocrine pancreas formation
      Title: Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nucleolar MIF4G domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044832.3 → NP_001038297.3  nucleolar MIF4G domain-containing protein 1 isoform 2

      Status: PROVISIONAL

      Source sequence(s)
      BX247878
      UniProtKB/TrEMBL
      A0A8M1N9E8, Q1LY16
      Related
      ENSDARP00000078588.4, ENSDART00000084153.6

    2. NM_001328060.1 → NP_001314989.1  nucleolar MIF4G domain-containing protein 1 isoform 1

      Status: PROVISIONAL

      Source sequence(s)
      BX247878
      UniProtKB/TrEMBL
      A0A8M1P9G3, Q1LY17
      Related
      ENSDARP00000122404.2, ENSDART00000142315.4
      Conserved Domains (3) summary
      smart00543
      Location:335 → 532
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
      cl02653
      Location:629 → 735
      MA3; MA3 domain
      cl08298
      Location:99 → 246
      NAP; Nucleosome assembly protein (NAP)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      40644872..40657791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394715.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      120042..132961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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