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    smap2 small ArfGAP2 [ Danio rerio (zebrafish) ]

    Gene ID: 556132, updated on 2-Nov-2024

    Summary

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    Official Symbol
    smap2provided by ZNC
    Official Full Name
    small ArfGAP2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-374
    See related
    Ensembl:ENSDARG00000061446 AllianceGenome:ZFIN:ZDB-GENE-060503-374
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-89d7.2
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in regulation of clathrin-dependent endocytosis. Predicted to be active in cytoplasm. Orthologous to human SMAP2 (small ArfGAP2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See smap2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (38386292..38419575, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (38798986..38832455, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene PHD finger protein 14 Neighboring gene uncharacterized LOC137488540 Neighboring gene procollagen, type IX, alpha 2 Neighboring gene uncharacterized LOC137488541

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of clathrin-dependent endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    stromal membrane-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044795.1 → NP_001038260.1  stromal membrane-associated protein 2

      See identical proteins and their annotated locations for NP_001038260.1

      Status: PROVISIONAL

      Source sequence(s)
      BX276085
      UniProtKB/TrEMBL
      B7ZVB7, Q1LXU3
      Related
      ENSDARP00000082073.4, ENSDART00000087639.5
      Conserved Domains (2) summary
      COG5347
      Location:13 → 275
      COG5347; GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport [Intracellular trafficking and secretion]
      pfam01412
      Location:13 → 115
      ArfGap; Putative GTPase activating protein for Arf

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      38386292..38419575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159676.5 → XP_005159733.1  stromal membrane-associated protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B6J1
      Conserved Domains (2) summary
      COG5347
      Location:17 → 257
      COG5347; GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport [Intracellular trafficking and secretion]
      pfam01412
      Location:16 → 97
      ArfGap; Putative GTPase activating protein for Arf
    Nucleotide Protein Strain
    Heading Accession and Version

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