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    rabgap1l RAB GTPase activating protein 1-like [ Danio rerio (zebrafish) ]

    Gene ID: 555272, updated on 17-Aug-2024

    Summary

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    Official Symbol
    rabgap1lprovided by ZNC
    Official Full Name
    RAB GTPase activating protein 1-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-389
    See related
    Ensembl:ENSDARG00000061757 AllianceGenome:ZFIN:ZDB-GENE-050208-389
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-197g15.12
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to act upstream of or within positive regulation of GTPase activity. Orthologous to human RABGAP1L (RAB GTPase activating protein 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See rabgap1l in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (17312066..17454463)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (17278718..17429475)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene tudor domain containing 5 Neighboring gene family with sequence similarity 163 member Ab Neighboring gene G protein-coupled receptor 52 Neighboring gene si:ch211-197g15.9 Neighboring gene interferon induced protein 44f1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables small GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    rab GTPase-activating protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      17312066..17454463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469587.1 → XP_021325262.1  rab GTPase-activating protein 1-like

      UniProtKB/TrEMBL
      A0A8M9P4Q6
      Related
      ENSDARP00000082893.5, ENSDART00000088460.7
      Conserved Domains (4) summary
      cd01211
      Location:157 → 285
      PTB_Rab6GAP; GTPase activating protein for Rab 6 Phosphotyrosine-binding (PTB) domain
      pfam00566
      Location:565 → 768
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12473
      Location:319 → 450
      DUF3694; Kinesin protein
      cl25732
      Location:784 → 1042
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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