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    cldn1 claudin 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 548421, updated on 4-Nov-2024

    Summary

    Official Symbol
    cldn1provided by Xenbase
    Official Full Name
    claudin 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-951609
    See related
    Ensembl:ENSXETG00000015050 AllianceGenome:Xenbase:XB-GENE-951609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    cld1; semp1; ilvasc; claudin-1
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in bicellular tight junction and plasma membrane. Human ortholog(s) of this gene implicated in Crohn's disease and atopic dermatitis. Orthologous to human CLDN1 (claudin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See cldn1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (104239965..104251374, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (99661786..99673139)

    Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene tumor protein p63 Neighboring gene prolyl 3-hydroxylase 2 Neighboring gene claudin 16 Neighboring gene transmembrane protein 207

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC107808

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015704.1NP_001015704.1  claudin-1

      See identical proteins and their annotated locations for NP_001015704.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089635
      UniProtKB/TrEMBL
      F7DGK9, Q5FW44
      Related
      ENSXETP00000032934.3, ENSXETT00000032934.5
      Conserved Domains (1) summary
      cl21598
      Location:5182
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      104239965..104251374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)