echdc1 ethylmalonyl-CoA decarboxylase 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: echdc1provided by Xenbase
Official Full Name: ethylmalonyl-CoA decarboxylase 1provided by Xenbase
Primary source: Xenbase:XB-GENE-958554
See related: Ensembl:ENSXETG00000010628 AllianceGenome:Xenbase:XB-GENE-958554
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: MMCD
Summary: Predicted to enable carboxy-lyase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human ECHDC1 (ethylmalonyl-CoA decarboxylase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	5	NC_030681.2 (67911208..67925487, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	5	NC_030681.1 (46549916..46566284)

Chromosome 5 - NC_030681.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables carboxy-lyase activity	ISS Inferred from Sequence or Structural Similarity more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables methyl/ethyl malonyl-CoA decarboxylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ethylmalonyl-CoA decarboxylase

Names: Enoyl-CoA hydratase domain-containing protein 1; Methylmalonyl-CoA decarboxylase; enoyl CoA hydratase domain containing 1; enoyl Coenzyme A hydratase domain containing 1

NP_001037862.1

EC 4.1.1.94

XP_031757537.1

EC 4.1.1.94

XP_031757538.1

EC 4.1.1.94

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044397.1 → NP_001037862.1 ethylmalonyl-CoA decarboxylase

See identical proteins and their annotated locations for NP_001037862.1

Status: PROVISIONAL

Source sequence(s)

CR942395

UniProtKB/Swiss-Prot

F6UNG1, Q0VFD0, Q28C91, Q5M791

UniProtKB/TrEMBL

A0A803J706, A0A8J1JI46

Related

ENSXETP00000061979.2, ENSXETT00000064480.3

Conserved Domains (1) summary

cd06558
Location:55 → 242

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

67911208..67925487 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_031901677.1 → XP_031757537.1 ethylmalonyl-CoA decarboxylase isoform X1

UniProtKB/TrEMBL

A0A803J706, A0A803JQY9

Related

ENSXETP00000110428.1, ENSXETT00000109887.1

Conserved Domains (1) summary

cd06558
Location:86 → 273

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
XM_031901678.1 → XP_031757538.1 ethylmalonyl-CoA decarboxylase isoform X2

UniProtKB/Swiss-Prot

F6UNG1, Q0VFD0, Q28C91, Q5M791

UniProtKB/TrEMBL

A0A803J706, A0A8J1JI46

Conserved Domains (1) summary

cd06558
Location:55 → 242

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...