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    pacsin2 protein kinase C and casein kinase substrate in neurons 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 496460, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pacsin2provided by Xenbase
    Official Full Name
    protein kinase C and casein kinase substrate in neurons 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-489578
    See related
    Ensembl:ENSXETG00000003264
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    sdpii; pacsin1; x-PACSIN2
    Orthologs
    human mouse all
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    Genomic context

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    See pacsin2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (3830429..3869302)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683549.1 (1495..36251)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene malonyl-CoA-acyl carrier protein transacylase Neighboring gene tubulin tyrosine ligase like 1 Neighboring gene ADP ribosylation factor GTPase activating protein 3 Neighboring gene alpha 1,4-galactosyltransferase (P blood group)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within caveola assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within plasma membrane tubulation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in caveola IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in recycling endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein kinase C and casein kinase substrate in neurons protein 2
    Names
    protein kinase C and casein kinase substrate in neurons 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011050.1 → NP_001011050.1  protein kinase C and casein kinase substrate in neurons protein 2

      See identical proteins and their annotated locations for NP_001011050.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084175
      UniProtKB/TrEMBL
      A0A6I8RYV8, A0A6I8S743, A0A803KJE1
      Related
      ENSXETP00000103264.1, ENSXETT00000120579.1
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:420 → 475
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      3830429..3869302
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031897869.1 → XP_031753729.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A6I8S743, A0A8J1J9M7
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:422 → 477
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    2. XM_031897872.1 → XP_031753732.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A6I8S743, A0A803J5I3
      Related
      ENSXETP00000103094.1, ENSXETT00000113567.1
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:387 → 442
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    3. XM_031897871.1 → XP_031753731.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A6I8S743, F6WFN4, Q5XH97
      Related
      ENSXETP00000007087.4, ENSXETT00000007087.4
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:389 → 444
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    4. XM_031897870.1 → XP_031753730.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A6I8S743, A0A8J1J9M7
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:422 → 477
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
    Nucleotide Protein Strain
    Heading Accession and Version

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