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    cdk2ap2 cyclin dependent kinase 2 associated protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 494160, updated on 2-Nov-2024

    Summary

    Official Symbol
    cdk2ap2provided by ZNC
    Official Full Name
    cyclin dependent kinase 2 associated protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-35
    See related
    Ensembl:ENSDARG00000103145 AllianceGenome:ZFIN:ZDB-GENE-040718-35
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92182
    Summary
    Predicted to enable kinase activity. Predicted to be involved in negative regulation of G1/S transition of mitotic cell cycle and regulation of microtubule cytoskeleton organization. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm; microtubule; and nucleus. Orthologous to human CDK2AP2 (cyclin dependent kinase 2 associated protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See cdk2ap2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (40009874..40015779, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39291801..39297737, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene superoxide dismutase 3, extracellular b Neighboring gene inhibitor of growth family, member 2 Neighboring gene aryl hydrocarbon receptor interacting protein Neighboring gene leucine-rich repeat LGI family, member 2b Neighboring gene coiled-coil domain containing 149b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in negative regulation of G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cyclin-dependent kinase 2-associated protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009898.1NP_001009898.1  cyclin-dependent kinase 2-associated protein 2

      See identical proteins and their annotated locations for NP_001009898.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075917
      UniProtKB/TrEMBL
      A0A0R4IXM4, A0A8M1N3R8, Q6DHQ0
      Related
      ENSDARP00000141347.2, ENSDART00000165373.2
      Conserved Domains (1) summary
      pfam09806
      Location:58110
      CDK2AP; Cyclin-dependent kinase 2-associated protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      40009874..40015779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009292801.4XP_009291076.1  cyclin-dependent kinase 2-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_009291076.1

      UniProtKB/TrEMBL
      A0A0R4IXM4, A0A8M1N3R8, Q6DHQ0
      Conserved Domains (1) summary
      pfam09806
      Location:58110
      CDK2AP; Cyclin-dependent kinase 2-associated protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394500.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1011..2176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)