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    med19b mediator complex subunit 19b [ Danio rerio (zebrafish) ]

    Gene ID: 445021, updated on 17-Aug-2024

    Summary

    Official Symbol
    med19bprovided by ZNC
    Official Full Name
    mediator complex subunit 19bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040727-4
    See related
    Ensembl:ENSDARG00000009472 AllianceGenome:ZFIN:ZDB-GENE-040727-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    med19; lcmr1l; zgc:110121
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED19 (mediator complex subunit 19). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (44582369..44591486)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (43881066..43890183)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 5a Neighboring gene thioredoxin-related transmembrane protein 2b Neighboring gene solute carrier family 43 member 1b Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene si:dkey-28b4.8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC110121

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 19-B
    Names
    mediator complex subunit 19-B
    mediator of RNA polymerase II transcription, subunit 19 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003416.2NP_001003416.2  mediator of RNA polymerase II transcription subunit 19-B

      See identical proteins and their annotated locations for NP_001003416.2

      Status: PROVISIONAL

      Source sequence(s)
      BC092743
      UniProtKB/Swiss-Prot
      Q568S3, Q6DRL8
      UniProtKB/TrEMBL
      B2GRD6
      Related
      ENSDARP00000016407.7, ENSDART00000003022.10
      Conserved Domains (1) summary
      pfam10278
      Location:60229
      Med19; Mediator of RNA pol II transcription subunit 19

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      44582369..44591486
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)