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    CG6136 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41877, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG6136provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038332
    Locus tag
    Dmel_CG6136
    See related
    AllianceGenome:FB:FBgn0038332
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    dCutC; Dmel\CG6136
    Summary
    Predicted to enable copper ion binding activity. Is expressed in organism. Orthologous to human CUTC (cutC copper transporter). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG6136 in Genome Data Viewer
    Location:
    88F2-88F2; 3-57 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15370036..15372212, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11195758..11197934, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cerebral cavernous malformation 3 Neighboring gene RIM-binding protein Neighboring gene heineken-cup Neighboring gene antisense RNA:CR46058 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fragile X protein functions with lgl and the par complex in flies and mice. Zarnescu DC, et al. Dev Cell, 2005 Jan. PMID 15621528
    2. Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease. Soriano S, et al. PLoS One, 2016. PMID 27433942, Free PMC Article
    3. Gene expression variation underlying tissue-specific responses to copper stress in Drosophila melanogaster. Everman ER, et al. G3 (Bethesda), 2024 Mar 6. PMID 38262701, Free PMC Article
    4. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article
    5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables copper ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6136-PB
    CG6136-PC
    CG6136-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15370036..15372212 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275671.1 → NP_001262600.1  uncharacterized protein Dmel_CG6136, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262600.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VF71
      UniProtKB/TrEMBL
      A0A0B4JDE8
      Conserved Domains (1) summary
      COG3142
      Location:10 → 259
      CutC; Copper homeostasis protein CutC [Inorganic ion transport and metabolism]

    2. NM_142203.4 → NP_650460.1  uncharacterized protein Dmel_CG6136, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650460.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VF71
      UniProtKB/TrEMBL
      A0A0B4JDE8
      Related
      FBpp0292328
      Conserved Domains (1) summary
      COG3142
      Location:10 → 259
      CutC; Copper homeostasis protein CutC [Inorganic ion transport and metabolism]

    3. NM_001202295.2 → NP_001189224.1  uncharacterized protein Dmel_CG6136, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189224.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VF71
      UniProtKB/TrEMBL
      A0A0B4JDE8
      Conserved Domains (1) summary
      COG3142
      Location:10 → 259
      CutC; Copper homeostasis protein CutC [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JDE8 A0A0B4JDE8
    Q9VF71.1 Q9VF71

    Gene LinkOut

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