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    CG1208 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40727, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG1208provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037386
    Locus tag
    Dmel_CG1208
    See related
    AllianceGenome:FB:FBgn0037386
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1208
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in adult head. Orthologous to human SLC2A6 (solute carrier family 2 member 6) and SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG1208 in Genome Data Viewer
    Location:
    83C4-83C5; 3-47.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5831639..5838782)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1657361..1664504)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Secretory 20 Neighboring gene degringolade Neighboring gene globin 3 Neighboring gene antisense RNA:CR45192 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The hemoglobin genes of Drosophila. Burmester T, et al. FEBS J, 2006 Feb. PMID 16420471
    2. Functional genomics of the evolution of increased resistance to parasitism in Drosophila. Wertheim B, et al. Mol Ecol, 2011 Mar. PMID 21062384
    3. Circulating glucose levels inversely correlate with Drosophila larval feeding through insulin signaling and SLC5A11. Ugrankar R, et al. Commun Biol, 2018. PMID 30271990, Free PMC Article
    4. Inter- and intra-species variation in genome-wide gene expression of Drosophila in response to parasitoid wasp attack. Salazar-Jaramillo L, et al. BMC Genomics, 2017 Apr 27. PMID 28449654, Free PMC Article
    5. The Drosophila blood-brain barrier: development and function of a glial endothelium. Limmer S, et al. Front Neurosci, 2014. PMID 25452710, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: 5836463-5836652 mobile_element_type = transposon:INE-1{}5694

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1208-PB
    CG1208-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5831639..5838782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141341.3 → NP_649598.1  uncharacterized protein Dmel_CG1208, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649598.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0T6, Q9VNJ1
      Related
      FBpp0112108
      Conserved Domains (2) summary
      cd06174
      Location:90 → 476
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:90 → 437
      MFS_1; Major Facilitator Superfamily

    2. NM_001104222.2 → NP_001097692.1  uncharacterized protein Dmel_CG1208, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097692.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JQU1
      Conserved Domains (2) summary
      cd06174
      Location:96 → 482
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:96 → 443
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JQU1 A8JQU1
    Q8T0T6 Q8T0T6

    Gene LinkOut

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