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    CG7650 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39694, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG7650provided by FlyBase
    Primary source
    FLYBASE:FBgn0036519
    Locus tag
    Dmel_CG7650
    See related
    AllianceGenome:FB:FBgn0036519
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT27057; Dmel\CG7650
    Summary
    Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Orthologous to several human genes including PDCL (phosducin like). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    71E2-71E2; 3-43 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15608707..15610386, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15601807..15603486, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene aaRS-interacting multifunctional protein 2 Neighboring gene uncharacterized protein Neighboring gene Rho GTPase activating protein at 71E Neighboring gene uncharacterized protein Neighboring gene comm3 Neighboring gene Phaser

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Forward Genetic Approach to Mapping a P-Element Second Site Mutation Identifies DCP2 as a Novel Tumor Suppressor in Drosophila melanogaster. Mishra R, et al. G3 (Bethesda), 2020 Aug 5. PMID 32591349, Free PMC Article
    2. Changes in gene expression linked with adult reproductive diapause in a northern malt fly species: a candidate gene microarray study. Kankare M, et al. BMC Ecol, 2010 Feb 1. PMID 20122138, Free PMC Article
    3. Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Cox RT, et al. Dis Model Mech, 2009 Sep-Oct. PMID 19638420, Free PMC Article
    4. GWAS reveal a role for the central nervous system in regulating weight and weight change in response to exercise. Watanabe LP, et al. Sci Rep, 2021 Mar 4. PMID 33664357, Free PMC Article
    5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7650-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15608707..15610386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140529.3 → NP_648786.1  uncharacterized protein Dmel_CG7650 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648786.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T3W9, Q9VUR7
      Related
      FBpp0075344
      Conserved Domains (1) summary
      cd02987
      Location:60 → 267
      Phd_like_Phd; Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VUR7.2 Q9VUR7

    Gene LinkOut

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