lgals3 lectin, galactoside-binding, soluble, 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: lgals3provided by Xenbase
Official Full Name: lectin, galactoside-binding, soluble, 3provided by Xenbase
Primary source: Xenbase:XB-GENE-983743
See related: Ensembl:ENSXETG00000036683 AllianceGenome:Xenbase:XB-GENE-983743
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: galectin-3; palectin-3
Summary: Predicted to enable IgE binding activity and carbohydrate binding activity. Predicted to act upstream of or within RNA splicing. Predicted to be located in extracellular region. Predicted to be part of spliceosomal complex. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (104676931..104690370, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (84372263..84385711, complement)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables IgE binding	IEA Inferred from Electronic Annotation more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: galectin-3

Names: galectin 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_203655.1 → NP_988986.1 galectin-3

See identical proteins and their annotated locations for NP_988986.1

Status: PROVISIONAL

Source sequence(s)

BC061319

UniProtKB/TrEMBL

F6ZE50, Q28HJ1, Q6P8B0

Related

ENSXETP00000097669.2, ENSXETT00000083787.2

Conserved Domains (2) summary

TIGR01628
Location:61 → 136

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

smart00908
Location:129 → 252

Gal-bind_lectin; Galactoside-binding lectin