U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CG13516 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3885599, updated on 22-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG13516provided by FlyBase
    Primary source
    FLYBASE:FBgn0040658
    Locus tag
    Dmel_CG13516
    See related
    AllianceGenome:FB:FBgn0040658
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BP1036; Dmel\CG13516
    Summary
    Predicted to be involved in apoptotic process. Predicted to be located in Golgi apparatus and nucleoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to human LITAF (lipopolysaccharide induced TNF factor). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG13516 in Genome Data Viewer
    Location:
    58F7-58F7; 2-100 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22669145..22670622)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18556650..18558127)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45269 Neighboring gene long non-coding RNA:CR42868 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44761 Neighboring gene Ring and YY1 Binding Protein Neighboring gene Partner of paired

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Single amino-acid mutation in a Drosoph ila melanogaster ribosomal protein: An insight in uL11 transcriptional activity. Grunchec H, et al. PLoS One, 2022. PMID 35981051, Free PMC Article
    2. A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. López Y, et al. PLoS One, 2014. PMID 25153327, Free PMC Article
    3. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Yandell M, et al. Proc Natl Acad Sci U S A, 2005 Feb 1. PMID 15668397, Free PMC Article
    4. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG13516-PA
    CG13516-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22669145..22670622
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299812.1 → NP_001286741.1  uncharacterized protein Dmel_CG13516, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286741.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6N5, Q2PE16
      Conserved Domains (1) summary
      pfam10601
      Location:96 → 162
      zf-LITAF-like; LITAF-like zinc ribbon domain

    2. NM_001038877.3 → NP_001033966.1  uncharacterized protein Dmel_CG13516, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033966.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6N5, Q2PE16
      Conserved Domains (1) summary
      pfam10601
      Location:96 → 162
      zf-LITAF-like; LITAF-like zinc ribbon domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2PE16 Q2PE16

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools