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    CG7215 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772662, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG7215provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038571
    Locus tag
    Dmel_CG7215
    See related
    AllianceGenome:FB:FBgn0038571
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32920; Dmel\CG7215
    Summary
    Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in post-translational protein targeting to endoplasmic reticulum membrane and tail-anchored membrane protein insertion into ER membrane. Predicted to be part of BAT3 complex. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gut section; mesoderm; and visceral muscle primordium. Orthologous to several human genes including UBL4A (ubiquitin like 4A). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG7215 in Genome Data Viewer
    Location:
    90F4-90F4; 3-62 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18165442..18167273, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13991164..13992995, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cap binding protein 20 Neighboring gene Peroxiredoxin 5 Neighboring gene well-rounded Neighboring gene cadmus Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila peroxiredoxin 5 is the second gene in a dicistronic operon. Michalak K, et al. Biochem Biophys Res Commun, 2008 Apr 4. PMID 18211821, Free PMC Article
    2. Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State. Kobayashi H, et al. Mol Cell, 2019 Jan 3. PMID 30503771
    3. The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction. Viquez NM, et al. J Neurosci, 2006 Sep 6. PMID 16957085, Free PMC Article
    4. Post-transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading. Toledano-Katchalski H, et al. Development, 2007 Oct. PMID 17728343
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in post-translational protein targeting to endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tail-anchored membrane protein insertion into ER membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of BAT3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7215-PA
    CG7215-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18165442..18167273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142423.4 → NP_650680.1  uncharacterized protein Dmel_CG7215, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650680.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VEC8
      Conserved Domains (2) summary
      smart00213
      Location:1 → 72
      UBQ; Ubiquitin homologues
      pfam00240
      Location:6 → 72
      ubiquitin; Ubiquitin family

    2. NM_001170173.2 → NP_001163644.1  uncharacterized protein Dmel_CG7215, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163644.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VEC8
      Conserved Domains (2) summary
      smart00213
      Location:1 → 72
      UBQ; Ubiquitin homologues
      pfam00240
      Location:6 → 72
      ubiquitin; Ubiquitin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VEC8 Q9VEC8

    Gene LinkOut

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