U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    His2B:CG33902 histone H2B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772058, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    His2B:CG33902provided by FlyBase
    Official Full Name
    histone H2Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053902
    Locus tag
    Dmel_CG33902
    See related
    AllianceGenome:FB:FBgn0053902
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33902; Dmel\CG33902
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in chromatin organization. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC11 (H2B clustered histone 11); and H2BC12L (H2B clustered histone 12 like). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See His2B:CG33902 in Genome Data Viewer
    Location:
    39D4-39D4; 2-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21452211..21452805, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21452211..21452805, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H3 Neighboring gene histone H1 Neighboring gene histone H2A Neighboring gene small non-coding RNA 430c Neighboring gene histone H4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sequence of histone 2B of Drosophila melanogaster. Elgin SC, et al. Biochemistry, 1979 Dec 11. PMID 117830
    2. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Kusch T, et al. Science, 2004 Dec 17. PMID 15528408
    3. Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster. Leach TJ, et al. J Biol Chem, 2000 Jul 28. PMID 10801889
    4. SUMO-Enriched Proteome for Drosophila Innate Immune Response. Handu M, et al. G3 (Bethesda), 2015 Aug 18. PMID 26290570, Free PMC Article
    5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nucleosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of nucleosome TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone H2B
    Names
    CG33902-PA
    His2B:CG33902-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      21452211..21452805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032129.2 → NP_001027300.1  histone H2B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027300.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02283, Q4ABE1, Q9W5U7
      Conserved Domains (1) summary
      smart00427
      Location:33 → 121
      H2B; Histone H2B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P02283.2 P02283

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.