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    CG11961 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37221, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG11961provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034436
    Locus tag
    Dmel_CG11961
    See related
    AllianceGenome:FB:FBgn0034436
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11961-PA; Dmel\CG11961
    Summary
    Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. Is expressed in adult head; adult midgut progenitor cell; embryonic midgut chamber; embryonic/larval midgut; and gastric caecum. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG11961 in Genome Data Viewer
    Location:
    56D1-56D2; 2-89 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19357532..19363124)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15245037..15250629)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Rad, Gem/Kir family member 1 Neighboring gene uncharacterized protein Neighboring gene wurstfest Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Rogers RL, et al. Genetics, 2009 Jan. PMID 19015547, Free PMC Article
    2. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Rogers RL, et al. Mol Biol Evol, 2012 Feb. PMID 21771717, Free PMC Article
    3. Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila. Adryan B, et al. Genome Biol, 2007. PMID 17705839, Free PMC Article
    4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    5. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11961-PA
    CG11961-PB
    CG11961-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19357532..19363124
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137569.4 → NP_611413.2  uncharacterized protein Dmel_CG11961, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611413.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IH56
      Related
      FBpp0085707
      Conserved Domains (1) summary
      cd03875
      Location:67 → 371
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

    2. NM_001259489.2 → NP_001246418.1  uncharacterized protein Dmel_CG11961, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246418.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4U2G8
      Conserved Domains (1) summary
      cd03875
      Location:91 → 395
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

    3. NM_166342.2 → NP_725876.1  uncharacterized protein Dmel_CG11961, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725876.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4U2G8
      Related
      FBpp0085708
      Conserved Domains (1) summary
      cd03875
      Location:91 → 395
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4U2G8 Q4U2G8
    Q8IH56 Q8IH56

    Gene LinkOut

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