Tmt1b thiol methyltransferase 1B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tmt1bprovided by RGD
Official Full Name: thiol methyltransferase 1Bprovided by RGD
Primary source: RGD:1305205
See related: EnsemblRapid:ENSRNOG00000007927 AllianceGenome:RGD:1305205
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mettl7b; RGD1305205
Summary: Predicted to enable thiol S-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in cytosol; endoplasmic reticulum membrane; and lipid droplet. Orthologous to human TMT1B (thiol methyltransferase 1B). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Liver (RPKM 728.3), Kidney (RPKM 353.4) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

Location:: 7q11

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (1973334..1975980, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (1388876..1391526, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (3383876..3386522, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables S-adenosylmethionine-dependent methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables thiol S-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables thiol S-methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables thiol S-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in lipid droplet	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: thiol S-methyltransferase TMT1B

Names: ALDI; associated with lipid droplet protein 1; methyltransferase like 7B; methyltransferase-like protein 7B; thiol S-methyltransferase METTL7B

NP_001019447.1

EC 2.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.