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    Cyp6a19 Cytochrome P450 6a19 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36662, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Cyp6a19provided by FlyBase
    Official Full Name
    Cytochrome P450 6a19provided by FlyBase
    Primary source
    FLYBASE:FBgn0033979
    Locus tag
    Dmel_CG10243
    See related
    AllianceGenome:FB:FBgn0033979
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6a19; CG10243; Dmel\CG10243
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in organism. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6a19 in Genome Data Viewer
    Location:
    51D1-51D1; 2-73 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14877786..14879752)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10765291..10767257)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 6a17 Neighboring gene Cytochrome P450 6a23 Neighboring gene Cytochrome P450 6a9 Neighboring gene Cytochrome P450 6a20 Neighboring gene Cytochrome P450 6a21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Daborn PJ, et al. Insect Biochem Mol Biol, 2007 May. PMID 17456446
    2. Signatures of Insecticide Selection in the Genome of Drosophila melanogaster. Duneau D, et al. G3 (Bethesda), 2018 Nov 6. PMID 30190420, Free PMC Article
    3. Male specific expression of a cytochrome P450 (Cyp312a1) in Drosophila melanogaster. Kasai S, et al. Biochem Biophys Res Commun, 2003 Jan 24. PMID 12559957
    4. Feminization of pheromone-sensing neurons affects mating decisions in Drosophila males. Lu B, et al. Biol Open, 2014 Feb 15. PMID 24463366, Free PMC Article
    5. Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans. Zhao L, et al. PLoS Genet, 2015 May. PMID 25950438, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 6a19
    Names
    CG10243-PA
    CG10243-PB
    Cyp6a19-PA
    Cyp6a19-PB
    NP_001286434.1
    NP_611001.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14877786..14879752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299505.1 → NP_001286434.1  cytochrome P450 6a19, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286434.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFE8, Q95RX9
      Conserved Domains (1) summary
      cl12078
      Location:32 → 362
      p450; Cytochrome P450

    2. NM_137157.4 → NP_611001.2  cytochrome P450 6a19, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611001.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82711
      UniProtKB/TrEMBL
      B6IDW1
      Related
      FBpp0086583
      Conserved Domains (1) summary
      pfam00067
      Location:32 → 495
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFE8 A0A0B4LFE8
    P82711.1 P82711
    Q95RX9 Q95RX9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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