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    ReepB Receptor expression enhancing protein B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36569, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ReepBprovided by FlyBase
    Official Full Name
    Receptor expression enhancing protein Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033906
    Locus tag
    Dmel_CG8331
    See related
    AllianceGenome:FB:FBgn0033906
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8331; CT24597; Dmel\CG8331
    Summary
    Involved in endoplasmic reticulum organization. Located in axon and endoplasmic reticulum. Is expressed in adult head; adult heart; and embryonic/larval salivary gland. Orthologous to human REEP5 (receptor accessory protein 5). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ReepB in Genome Data Viewer
    Location:
    50E1-50E1; 2-69 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14170462..14172998)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10057967..10060503)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44368 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene combgap Neighboring gene SAXO downstream of blistered

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics. Oliva MK, et al. Front Neurosci, 2020. PMID 32903680, Free PMC Article
    2. Evolution of three parent genes and their retrogene copies in Drosophila species. O'Neill RS, et al. Int J Evol Biol, 2013. PMID 23841016, Free PMC Article
    3. Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins. Yalçın B, et al. Elife, 2017 Jul 25. PMID 28742022, Free PMC Article
    4. Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair. Nakamura M, et al. PLoS Genet, 2020 Dec. PMID 33306674, Free PMC Article
    5. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of intracellular transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endomembrane system HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor expression enhancing protein B
    Names
    CG8331-PA
    CG8331-PB
    CG8331-PC
    CG8331-PD
    ReepB-PA
    ReepB-PB
    ReepB-PC
    ReepB-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14170462..14172998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201999.2 → NP_001188928.1  receptor expression enhancing protein B, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188928.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9M2, Q8T9H5
      Conserved Domains (1) summary
      pfam03134
      Location:63 → 151
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    2. NM_137092.4 → NP_610936.2  receptor expression enhancing protein B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610936.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9M2, Q8T9H5
      Related
      FBpp0086654
      Conserved Domains (1) summary
      pfam03134
      Location:63 → 151
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    3. NM_001201997.2 → NP_001188926.1  receptor expression enhancing protein B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188926.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0PPK4, F2FB55
      Conserved Domains (1) summary
      pfam03134
      Location:45 → 133
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    4. NM_001201998.2 → NP_001188927.1  receptor expression enhancing protein B, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188927.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD51, C0PPK4
      Conserved Domains (1) summary
      pfam03134
      Location:38 → 126
      TB2_DP1_HVA22; TB2/DP1, HVA22 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JD51 A0A0B4JD51
    A1Z9M2 A1Z9M2
    F2FB55 F2FB55
    Q8T9H5 Q8T9H5

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