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    Bahd1 bromo adjacent homology domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362194, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Bahd1provided by RGD
    Official Full Name
    bromo adjacent homology domain containing 1provided by RGD
    Primary source
    RGD:1563127
    See related
    EnsemblRapid:ENSRNOG00000010428 AllianceGenome:RGD:1563127
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563127
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in heterochromatin assembly and negative regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be part of chromatin silencing complex. Orthologous to human BAHD1 (bromo adjacent homology domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 55.1), Adrenal (RPKM 48.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bahd1 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (126341853..126368281)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (105891207..105914414)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (110708790..110732038)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene isovaleryl-CoA dehydrogenase Neighboring gene uncharacterized LOC134486300 Neighboring gene carbohydrate sulfotransferase 14 Neighboring gene uncharacterized LOC134486301

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Human BAHD1 promotes heterochromatic gene silencing. Bierne H, et al. Proc Natl Acad Sci U S A, 2009 Aug 18. PMID 19666599, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in heterochromatin formation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of chromatin silencing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of chromatin silencing complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    bromo adjacent homology domain-containing 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427253.1 → NP_001414182.1  bromo adjacent homology domain-containing 1 protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3
      Related
      ENSRNOP00000013878.6, ENSRNOT00000013878.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      126341853..126368281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284160.1 → XP_063140230.1  bromo adjacent homology domain-containing 1 protein isoform X4

      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3

    2. XM_006234794.4 → XP_006234856.1  bromo adjacent homology domain-containing 1 protein isoform X1

      See identical proteins and their annotated locations for XP_006234856.1

      Related
      ENSRNOP00000110984.1, ENSRNOT00000169242.1
      Conserved Domains (2) summary
      cd04714
      Location:624 → 734
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
      cl11396
      Location:250 → 363
      Patatin_and_cPLA2; Patatins and Phospholipases

    3. XM_017592196.3 → XP_017447685.2  bromo adjacent homology domain-containing 1 protein isoform X3

    4. XM_017592195.3 → XP_017447684.2  bromo adjacent homology domain-containing 1 protein isoform X2

    5. XM_017592197.2 → XP_017447686.1  bromo adjacent homology domain-containing 1 protein isoform X4

      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3
      Conserved Domains (3) summary
      PHA03247
      Location:93 → 369
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:226 → 562
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:615 → 725
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...

    6. XM_039106493.2 → XP_038962421.1  bromo adjacent homology domain-containing 1 protein isoform X4

      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3
      Conserved Domains (3) summary
      PHA03247
      Location:93 → 369
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:226 → 562
      PHA03307; transcriptional regulator ICP4; Provisional
      cd04714
      Location:615 → 725
      BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...

    7. XM_063284161.1 → XP_063140231.1  bromo adjacent homology domain-containing 1 protein isoform X4

      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3

    8. XM_063284162.1 → XP_063140232.1  bromo adjacent homology domain-containing 1 protein isoform X4

      UniProtKB/TrEMBL
      A6HPD4, D3ZHT3
    Nucleotide Protein Strain
    Heading Accession and Version

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