RAMACL RNA guanine-7 methyltransferase activating subunit like [Homo sapiens (human)] - Gene

Summary

Official Symbol: RAMACLprovided by HGNC
Official Full Name: RNA guanine-7 methyltransferase activating subunit likeprovided by HGNC
Primary source: HGNC:HGNC:21234
See related: Ensembl:ENSG00000235272 AllianceGenome:HGNC:21234
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: RAMMETL; C6orf119; RAMMETP1; FAM103A2P; dJ427A4.2
Summary: Predicted to enable RNA binding activity. Predicted to be involved in methylation. Predicted to be located in nucleus. Predicted to be part of mRNA capping enzyme complex. [provided by Alliance of Genome Resources, Oct 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 6q27

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	6	NC_000006.12 (166583009..166586678, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	6	NC_060930.1 (167961081..167964751, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	6	NC_000006.11 (166996497..167000166, complement)

Chromosome 6 - NC_000006.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA 5'-cap (guanine-N7)-methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of mRNA capping enzyme complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: RNA guanine-N7 methyltransferase-activating subunit-like protein

Names: RNA guanine-7 methyltransferase activating subunit like (pseudogene); RNMT activating mRNA cap methyltransferase subunit like (pseudogene); RNMT activating mRNA cap methyltransferase subunit pseudogene 1; family with sequence similarity 103 member A2, pseudogene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001395999.1 → NP_001382928.1 RNA guanine-N7 methyltransferase-activating subunit-like protein

Status: VALIDATED

Source sequence(s)

Z98049

Consensus CDS

CCDS94031.1

UniProtKB/Swiss-Prot

A0A3B3IU46

Related

ENSP00000498060.1, ENST00000444122.3

Conserved Domains (1) summary

pfam15320
Location:10 → 87

RAM; mRNA cap methylation, RNMT-activating mini protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000006.12 Reference GRCh38.p14 Primary Assembly

Range

166583009..166586678 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060930.1 Alternate T2T-CHM13v2.0

Range

167961081..167964751 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001012240.1: Suppressed sequence

Description

NM_001012240.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.