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    CG9150 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33856, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG9150provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031775
    Locus tag
    Dmel_CG9150
    See related
    AllianceGenome:FB:FBgn0031775
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9150
    Summary
    Predicted to enable 3-keto sterol reductase activity and steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Is expressed in adult head and eye. Orthologous to human DHRS11 (dehydrogenase/reductase 11). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG9150 in Genome Data Viewer
    Location:
    26B4-26B4; 2-18 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6067668..6068594, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6067668..6068594, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene uncharacterized protein Neighboring gene Prefoldin 1 Neighboring gene uncharacterized protein Neighboring gene Kruppel homolog 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Circadian deep sequencing reveals stress-response genes that adopt robust rhythmic expression during aging. Kuintzle RC, et al. Nat Commun, 2017 Feb 21. PMID 28221375, Free PMC Article
    2. Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation. Liu J, et al. Hereditas, 2022 Oct 21. PMID 36271387, Free PMC Article
    3. Inhibition of mevalonate pathway by macrophage-specific delivery of atorvastatin prevents their pro-inflammatory polarisation. Krejčová G, et al. Insect Mol Biol, 2024 Aug. PMID 38367277
    4. Identifying sleep regulatory genes using a Drosophila model of insomnia. Seugnet L, et al. J Neurosci, 2009 Jun 3. PMID 19494137, Free PMC Article
    5. Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Park SY, et al. Genetics, 2014 Feb. PMID 24281154, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 17-beta-hydroxysteroid dehydrogenase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables 17-beta-ketosteroid reductase (NADPH) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables 3-keto sterol reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9150-PB
    NP_608991.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6067668..6068594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135147.3 → NP_608991.2  uncharacterized protein Dmel_CG9150 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608991.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0IGY4, Q9VMH9
      Conserved Domains (2) summary
      COG4221
      Location:1 → 251
      YdfG; NADP-dependent 3-hydroxy acid dehydrogenase YdfG [Energy production and conversion]
      cl21454
      Location:1 → 247
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMH9 Q9VMH9

    Gene LinkOut

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