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    TrissinR Trissin receptor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33812, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TrissinRprovided by FlyBase
    Official Full Name
    Trissin receptorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085410
    Locus tag
    Dmel_CG34381
    See related
    AllianceGenome:FB:FBgn0085410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0170980.172; anon-WO0170980.173; CG14002; CG14003; CG14004; CG31645; CG34381; Dmel\CG34381; Trissin-R
    Old locus tag
    CG14004; CG31645; Dmel_CG14004; Dmel_CG31645
    Summary
    Enables G protein-coupled peptide receptor activity. Involved in G protein-coupled receptor signaling pathway. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See TrissinR in Genome Data Viewer
    Location:
    25F5-26A1; 2-18 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5824004..5856767)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5824004..5856767)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 6C-like Neighboring gene rau Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the endogenous cysteine-rich peptide trissin, a ligand for an orphan G protein-coupled receptor in Drosophila. Ida T, et al. Biochem Biophys Res Commun, 2011 Oct 14. PMID 21939639
    2. Antagonistic feedback loops involving Rau and Sprouty in the Drosophila eye control neuronal and glial differentiation. Sieglitz F, et al. Sci Signal, 2013 Nov 5. PMID 24194583
    3. Feeding and the rhodopsin family g-protein coupled receptors in nematodes and arthropods. Cardoso JC, et al. Front Endocrinol (Lausanne), 2012. PMID 23264768, Free PMC Article
    4. Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles. Radford JC, et al. J Biol Chem, 2002 Oct 11. PMID 12163486
    5. Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits. Ko KI, et al. Elife, 2015 Jul 24. PMID 26208339, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. an endogenous ligand cysteine-rich peptide "trissin" of the Drosophila orphan GPCR, CG34381, was identified.
      Title: Identification of the endogenous cysteine-rich peptide trissin, a ligand for an orphan G protein-coupled receptor in Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 5837184-5837224 mobile_element_type = transposon:INE-1{}5111

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables G protein-coupled peptide receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide receptor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trissin receptor
    Names
    CG34381-PB
    CG34381-PC
    CG34381-PD
    CG34381-PE
    TrissinR-PB
    TrissinR-PC
    TrissinR-PD
    TrissinR-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5824004..5856767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273179.2 → NP_001260108.1  trissin receptor, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260108.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PC39, Q2TVJ4
      Conserved Domains (2) summary
      pfam00001
      Location:201 → 385
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:191 → 327
      7tm_4; Olfactory receptor

    2. NM_001298712.1 → NP_001285641.1  trissin receptor, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285641.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2TVJ4, R4GRV6
      Conserved Domains (2) summary
      pfam00001
      Location:201 → 385
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:191 → 327
      7tm_4; Olfactory receptor

    3. NM_001103622.2 → NP_001097092.1  trissin receptor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097092.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VML9, Q9VMM1
      UniProtKB/TrEMBL
      Q2TVJ4
      Conserved Domains (2) summary
      pfam00001
      Location:201 → 385
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:191 → 327
      7tm_4; Olfactory receptor

    4. NM_135118.3 → NP_608962.3  trissin receptor, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608962.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2TVJ4, R4GRV6
      Conserved Domains (2) summary
      pfam00001
      Location:201 → 385
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:191 → 327
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PC39 M9PC39
    Q9VML9.4 Q9VML9
    R4GRV6 R4GRV6

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