CG3277 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG3277provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0031518
Locus tag: Dmel_CG3277
See related: AllianceGenome:FB:FBgn0031518
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG3277
Summary: Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including arteriovenous malformation; basal ganglia calcification; hematologic cancer (multiple); infantile myofibromatosis; and kidney cancer (multiple). Orthologous to human TEK (TEK receptor tyrosine kinase); PDGFRA (platelet derived growth factor receptor alpha); and PDGFRB (platelet derived growth factor receptor beta). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (3304100..3317418)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (3304100..3317418)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info
enables transmembrane receptor protein tyrosine kinase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in multicellular organism development	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of receptor complex	IBA Inferred from Biological aspect of Ancestor more info

NP_608762.3

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The following sections contain reference sequences that belong to a specific genome build. Explain