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    dpr2 defective proboscis extension response 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3346227, updated on 2-Nov-2024

    Summary

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    Official Symbol
    dpr2provided by FlyBase
    Official Full Name
    defective proboscis extension response 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0261871
    Locus tag
    Dmel_CG33507
    See related
    AllianceGenome:FB:FBgn0261871
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BP1042; CG14067; CG14068; CG33507; CT33638; Dmel\CG33507; Dpr-2; Dpr2; Flk
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See dpr2 in Genome Data Viewer
    Location:
    32B4-32C1; 2-44 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10917015..10964153, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10917015..10964153, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44492 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44493 Neighboring gene Transmembrane protein 214 Neighboring gene YL-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Widespread polymorphism in the positions of stop codons in Drosophila melanogaster. Lee YC, et al. Genome Biol Evol, 2012. PMID 22051795, Free PMC Article
    2. Modular transcriptional programs separately define axon and dendrite connectivity. Kurmangaliyev YZ, et al. Elife, 2019 Nov 5. PMID 31687928, Free PMC Article
    3. Specification of Dendritogenesis Site in Drosophila aCC Motoneuron by Membrane Enrichment of Pak1 through Dscam1. Kamiyama D, et al. Dev Cell, 2015 Oct 12. PMID 26460947, Free PMC Article
    4. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
    5. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defective proboscis extension response 2
    Names
    BP1042
    CG33507-PF
    CG33507-PG
    dpr2-PF
    dpr2-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10917015..10964153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169474.3 → NP_001162945.3  defective proboscis extension response 2, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162945.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHE8, Q59DZ4
      Conserved Domains (3) summary
      smart00410
      Location:113 → 206
      IG_like; Immunoglobulin like
      pfam00047
      Location:220 → 306
      ig; Immunoglobulin domain
      cl11960
      Location:116 → 192
      Ig; Immunoglobulin domain

    2. NM_001014480.4 → NP_001014480.4  defective proboscis extension response 2, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014480.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHE8, Q59DZ4
      Conserved Domains (3) summary
      smart00410
      Location:113 → 206
      IG_like; Immunoglobulin like
      pfam00047
      Location:220 → 306
      ig; Immunoglobulin domain
      cl11960
      Location:116 → 192
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q59DZ4 Q59DZ4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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