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    CG3515 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33437, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG3515provided by FlyBase
    Primary source
    FLYBASE:FBgn0031431
    Locus tag
    Dmel_CG3515
    See related
    AllianceGenome:FB:FBgn0031431
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3515
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in histone H3-K4 trimethylation. Predicted to be part of Set1C/COMPASS complex. Orthologous to human WDR82 (WD repeat domain 82). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    22F4-22F4; 2-6 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2551145..2552825, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2551145..2552825, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46069 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44112 Neighboring gene long non-coding RNA:CR44113 Neighboring gene Cytochrome P450 309a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Suppressor of sable [Su(s)] and Wdr82 down-regulate RNA from heat-shock-inducible repetitive elements by a mechanism that involves transcription termination. Brewer-Jensen P, et al. RNA, 2016 Jan. PMID 26577379, Free PMC Article
    2. Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Engström PG, et al. Genome Res, 2007 Dec. PMID 17989259, Free PMC Article
    3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3515-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2551145..2552825 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134843.3 → NP_608687.2  uncharacterized protein Dmel_CG3515 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608687.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3W2, Q9VQD1
      Related
      FBpp0077430
      Conserved Domains (3) summary
      COG2319
      Location:31 → 309
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:28 → 62
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:28 → 309
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3W2 Q8T3W2
    Q9VQD1 Q9VQD1

    Gene LinkOut

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