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    CG7889 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32916, updated on 19-Jun-2024

    Summary

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    Official Symbol
    CG7889provided by FlyBase
    Primary source
    FLYBASE:FBgn0031003
    Locus tag
    Dmel_CG7889
    See related
    AllianceGenome:FB:FBgn0031003
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7889
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Is expressed in anterior endoderm; anterior midgut primordium; embryonic/larval midgut; organism; and posterior midgut primordium. Orthologous to several human genes including EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG7889 in Genome Data Viewer
    Location:
    18B4-18B4; 1-62 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19243631..19245224)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19137664..19139257)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Heparan sulfate 3-O sulfotransferase-B Neighboring gene rapamycin-insensitive companion of Tor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi. Axelsson E, et al. BMC Bioinformatics, 2011 Aug 17. PMID 21849035, Free PMC Article
    2. Variation in the response to exercise stimulation in Drosophila: marathon runner versus sprinter genotypes. Riddle NC. J Exp Biol, 2020 Sep 21. PMID 32737212
    3. The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster. Sitnik JL, et al. Genetics, 2016 Mar. PMID 26746709, Free PMC Article
    4. Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. Francis D, et al. G3 (Bethesda), 2021 Sep 27. PMID 34568906, Free PMC Article
    5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-lysine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in peptidyl-lysine methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of protein-containing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7889-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      19243631..19245224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133140.3 → NP_573368.2  uncharacterized protein Dmel_CG7889 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573368.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYQ1, Q9VWJ9
      Related
      FBpp0074446
      Conserved Domains (2) summary
      pfam14904
      Location:8 → 83
      FAM86; Family of unknown function
      cl17173
      Location:112 → 249
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYQ1 Q8SYQ1
    Q9VWJ9 Q9VWJ9

    Gene LinkOut

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