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    ets2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 [ Danio rerio (zebrafish) ]

    Gene ID: 326672, updated on 28-Oct-2024

    Summary

    Official Symbol
    ets2provided by ZNC
    Official Full Name
    v-ets avian erythroblastosis virus E26 oncogene homolog 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-552
    See related
    Ensembl:ENSDARG00000103980 AllianceGenome:ZFIN:ZDB-GENE-050522-552
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92106; wu:fe02h08; wu:fk74c05
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in endothelial cell; head; lateral plate mesoderm; and margin. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See ets2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (187780..196815)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (187745..196815)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene potassium inwardly rectifying channel subfamily J member 15 Neighboring gene ETS transcription factor ERG Neighboring gene U1 spliceosomal RNA Neighboring gene proteasome (prosome, macropain) assembly chaperone 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein C-ets-2
    Names
    avian leukemia oncogene 2
    v-ets erythroblastosis virus E26 oncogene homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001023580.1NP_001018874.1  protein C-ets-2

      See identical proteins and their annotated locations for NP_001018874.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095899
      UniProtKB/TrEMBL
      A0A8M1N6I5, Q501S1
      Related
      ENSDARP00000131539.1, ENSDART00000161007.1
      Conserved Domains (2) summary
      smart00413
      Location:332416
      ETS; erythroblast transformation specific domain
      cl15755
      Location:76164
      SAM_superfamily; SAM (Sterile alpha motif )

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      187780..196815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223726.1XP_068079827.1  protein C-ets-2 isoform X1