pdcl phosducin-like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pdclprovided by ZNC
Official Full Name: phosducin-likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2365
See related: Ensembl:ENSDARG00000009480 AllianceGenome:ZFIN:ZDB-GENE-030131-2365
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc06a08; zgc:73264; im:6793474; wu:fc06a08
Summary: Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway and visual perception. Is expressed in central nervous system; olfactory placode; and trigeminal placode. Orthologous to human PDCL (phosducin like). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (51950504..51966836, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (52093597..52109929, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb80h06.x1 (e-PCR)
- UniSTS:191588

fc15d07.x1 (e-PCR)
- UniSTS:192729

fc06a08.x1 (e-PCR)
- UniSTS:192226

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in heterotrimeric G-protein complex assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within visual perception	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosducin-like protein

NP_955941.2

EC 1.14.99.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199647.2 → NP_955941.2 phosducin-like protein

Status: VALIDATED

Source sequence(s)

CU655845, EH546236

UniProtKB/TrEMBL

A0A8M1PFM0, F1QTL0, X1WDC6

Related

ENSDARP00000128225.1, ENSDART00000153959.2

Conserved Domains (2) summary

cd02987
Location:52 → 273

Phd_like_Phd; Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes ...

pfam02114
Location:46 → 295

Phosducin; Phosducin