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    tcerg1a transcription elongation regulator 1a (CA150) [ Danio rerio (zebrafish) ]

    Gene ID: 323071, updated on 28-Oct-2024

    Summary

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    Official Symbol
    tcerg1aprovided by ZNC
    Official Full Name
    transcription elongation regulator 1a (CA150)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1791
    See related
    Ensembl:ENSDARG00000098822 AllianceGenome:ZFIN:ZDB-GENE-030131-1791
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tcerg1; wu:fb80g01
    Summary
    Predicted to enable RNA polymerase binding activity and transcription coregulator activity. Predicted to be active in nucleus. Orthologous to human TCERG1 (transcription elongation regulator 1). [provided by Alliance of Genome Resources, Oct 2024]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See tcerg1a in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (52481292..52518568)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (51765598..51802874)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like Neighboring gene exosome component 3 Neighboring gene protein phosphatase 2, regulatory subunit B, beta a Neighboring gene G protein-coupled receptor 151

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model. Daly C, et al. Sci Rep, 2017 Sep 12. PMID 28900183, Free PMC Article
    2. Transcriptome analysis of zebrafish embryogenesis using microarrays. Mathavan S, et al. PLoS Genet, 2005 Aug. PMID 16132083, Free PMC Article
    3. Common genetic control of haemangioblast and cardiac development in zebrafish. Peterkin T, et al. Development, 2009 May. PMID 19297410, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation regulator 1a
    Names
    transcription elongation regulator 1 (CA150)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198357.3 → NP_938171.2  transcription elongation regulator 1a

      Status: VALIDATED

      Source sequence(s)
      AL954718, CN506442, FP628471
      UniProtKB/TrEMBL
      A0A8M1PCM8
      Related
      ENSDARP00000139470.1, ENSDART00000164281.2
      Conserved Domains (6) summary
      smart00441
      Location:857 → 912
      FF; Contains two conserved F residues
      smart00456
      Location:450 → 478
      WW; Domain with 2 conserved Trp (W) residues
      pfam00397
      Location:351 → 378
      WW; WW domain
      pfam01846
      Location:562 → 611
      FF; FF domain
      pfam06346
      Location:194 → 334
      Drf_FH1; Formin Homology Region 1
      pfam11825
      Location:217 → 334
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      52481292..52518568
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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