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    CG32687 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31980, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG32687provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052687
    Locus tag
    Dmel_CG32687
    See related
    AllianceGenome:FB:FBgn0052687
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH29237; CG2143; CG2892; Cg32687; CT6984; CT7080; Dmel\CG32687
    Summary
    Predicted to be involved in intracellular signal transduction. Is expressed in embryonic/larval fat body; embryonic/larval midgut; embryonic/larval posterior spiracle; yolk; and yolk nucleus. Orthologous to human LRRC58 (leucine rich repeat containing 58). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG32687 in Genome Data Viewer
    Location:
    9D2-9D2; 1-32 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10482028..10487205, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10376061..10381238, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Protein phosphatase 4 regulatory subunit 2-related protein Neighboring gene sprint Neighboring gene uncharacterized protein Neighboring gene Rab at 9D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A rapidly evolving MYB-related protein causes species isolation in Drosophila. Barbash DA, et al. Proc Natl Acad Sci U S A, 2003 Apr 29. PMID 12695567, Free PMC Article
    2. RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. Asensio CS, et al. J Cell Biol, 2010 Dec 13. PMID 21149569, Free PMC Article
    3. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Wang T, et al. Proc Natl Acad Sci U S A, 2021 Mar 23. PMID 33723074, Free PMC Article
    4. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    5. Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response. Zinke I, et al. EMBO J, 2002 Nov 15. PMID 12426388, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32687-PA
    CG32687-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10482028..10487205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272483.1 → NP_001259412.1  uncharacterized protein Dmel_CG32687, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259412.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U2
      Conserved Domains (3) summary
      sd00033
      Location:72 → 92
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:134 → 171
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:132 → 190
      LRR_8; Leucine rich repeat

    2. NM_167233.2 → NP_727428.1  uncharacterized protein Dmel_CG32687, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U2
      Related
      FBpp0071392
      Conserved Domains (3) summary
      sd00033
      Location:72 → 92
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:134 → 171
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:132 → 190
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2U2 Q9W2U2

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