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    serp-1.2 [ Caenorhabditis elegans ]

    Gene ID: 259582, updated on 22-Aug-2024

    Summary

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    Official Symbol
    serp-1.2
    Primary source
    WormBase:WBGene00020374
    Locus tag
    CELE_T09A12.5
    See related
    AllianceGenome:WB:WBGene00020374
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endoplasmic reticulum unfolded protein response and protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Orthologous to human SERP1 (stress associated endoplasmic reticulum protein 1) and SERP2 (stress associated endoplasmic reticulum protein family member 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (8225674..8226352)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ion transport domain-containing protein Neighboring gene Glutathione peroxidase Neighboring gene Nuclear hormone receptor family member nhr-66 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene AraC family transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Stress-associated endoplasmic reticulum protein
    NP_741461.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8225674..8226352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171395.10 → NP_741461.1  Stress-associated endoplasmic reticulum protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MXH3
      Conserved Domains (1) summary
      pfam06624
      Location:2 → 58
      RAMP4; Ribosome associated membrane protein RAMP4
    Nucleotide Protein
    Heading Accession and Version

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