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    asc1 methionyl and glutamyl-tRNA synthetase cofactor [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543087, updated on 18-Sep-2024

    Summary

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    Official Symbol
    asc1
    Official Full Name
    methionyl and glutamyl-tRNA synthetase cofactor
    Primary source
    PomBase:SPAC30C2.04
    Locus tag
    SPOM_SPAC30C2.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See asc1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4638103..4639647)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene deoxyhypusine hydroxylase Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene cornichon family protein Erv14 Neighboring gene ncRNA Neighboring gene GTPase dml1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission Yeast Asc1 Stabilizes the Interaction between Eukaryotic Initiation Factor 3a and Rps0A/uS2 for Protein Synthesis. Wang YT, et al. Mol Cell Biol, 2019 Oct 1. PMID 31285271, Free PMC Article
    2. Fission Yeast Puf2, a Pumilio and FBF Family RNA-Binding Protein, Links Stress Granules to Processing Bodies. Hsiao WY, et al. Mol Cell Biol, 2020 Apr 13. PMID 32071154, Free PMC Article
    3. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
    4. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article
    5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables tRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA aminoacylation for protein translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic stress granule EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of eukaryotic 43S preinitiation complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of methionyl glutamyl tRNA synthetase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of methionyl glutamyl tRNA synthetase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methionyl and glutamyl-tRNA synthetase cofactor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4638103..4639647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020085.3 → NP_594656.1  methionyl and glutamyl-tRNA synthetase cofactor [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594656.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6K7
      Conserved Domains (2) summary
      cd10289
      Location:104 → 183
      GST_C_AaRS_like; Glutathione S-transferase C-terminal-like, alpha helical domain of various Aminoacyl-tRNA synthetases and similar domains
      cd02799
      Location:277 → 382
      tRNA_bind_EMAP-II_like; tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae ...
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials