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    psm3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543010, updated on 22-Aug-2024

    Summary

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    Official Symbol
    psm3
    Primary source
    PomBase:SPAC10F6.09c
    Locus tag
    SPOM_SPAC10F6.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    smc3
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    Genomic context

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    See psm3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1220969..1224858, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein mug94 Neighboring gene ncRNA Neighboring gene Ino80 complex HMG box subunit Nht1 Neighboring gene RIO family protein kinase Neighboring gene autophagy-associated protein kinase activator Atg17 Neighboring gene ncRNA Neighboring gene protein-S isoprenylcysteine O-methyltransferase Mam4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Folco HD, et al. Curr Biol, 2015 Feb 2. PMID 25619765, Free PMC Article
    2. Psm3 acetylation on conserved lysine residues is dispensable for viability in fission yeast but contributes to Eso1-mediated sister chromatid cohesion by antagonizing Wpl1. Feytout A, et al. Mol Cell Biol, 2011 Apr. PMID 21300781, Free PMC Article
    3. DNA Binding by the Mis4(Scc2) Loader Promotes Topological DNA Entrapment by the Cohesin Ring. Kurokawa Y, et al. Cell Rep, 2020 Nov 10. PMID 33176147
    4. Acetylation regulates monopolar attachment at multiple levels during meiosis I in fission yeast. Kagami A, et al. EMBO Rep, 2011 Oct 28. PMID 21979813, Free PMC Article
    5. Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly. Sakai A, et al. EMBO J, 2003 Jun 2. PMID 12773391, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Psm3 acetylation contributes to Eso1 counteracting of Wpl1 to secure stable cohesin interaction with postreplicative chromosomes
      Title: Psm3 acetylation on conserved lysine residues is dispensable for viability in fission yeast but contributes to Eso1-mediated sister chromatid cohesion by antagonizing Wpl1.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    contributes_to double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin looping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in homologous chromosome orientation in meiotic metaphase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid cohesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    part_of meiotic cohesin complex NAS
    Non-traceable Author Statement
    more info
    		  
    part_of mitotic cohesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitotic cohesin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mitotic/meiotic cohesin complex ATPase subunit Psm3/Smc3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1220969..1224858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018657.3 → NP_593260.1  mitotic/meiotic cohesin complex ATPase subunit Psm3/Smc3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593260.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42649
      Conserved Domains (1) summary
      COG1196
      Location:1 → 1192
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version

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