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    psc3 mitotic cohesin complex non-SMC subunit Psc3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542387, updated on 18-Sep-2024

    Summary

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    Official Symbol
    psc3
    Official Full Name
    mitotic cohesin complex non-SMC subunit Psc3
    Primary source
    PomBase:SPAC17H9.20
    Locus tag
    SPOM_SPAC17H9.20
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC607.01
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    Genomic context

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    See psc3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003424.3 (2036295..2040544)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Mdm10/Mdm12/Mmm1 complex subunit Mdm10 Neighboring gene uncharacterized protein Neighboring gene WD repeat protein Cdt2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene U3 snoRNP-associated protein Snu13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast. Nonaka N, et al. Nat Cell Biol, 2002 Jan. PMID 11780129
    2. Bub3p facilitates spindle checkpoint silencing in fission yeast. Vanoosthuyse V, et al. Mol Biol Cell, 2009 Dec. PMID 19846658, Free PMC Article
    3. Hsk1-Dfp1 is required for heterochromatin-mediated cohesion at centromeres. Bailis JM, et al. Nat Cell Biol, 2003 Dec. PMID 14625560
    4. A Brownian ratchet model for DNA loop extrusion by the cohesin complex. Higashi TL, et al. Elife, 2021 Jul 26. PMID 34309513, Free PMC Article
    5. Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy. Folco HD, et al. Nature, 2017 Mar 2. PMID 28199302, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin looping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cohesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in condensed nuclear chromosome IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in mating-type region heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitotic cohesin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in subtelomeric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitotic cohesin complex non-SMC subunit Psc3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2036295..2040544
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356047.2 → NP_001343016.1  mitotic cohesin complex non-SMC subunit Psc3 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13816, Q38G50, Q9US16
      Conserved Domains (1) summary
      cl26728
      Location:1 → 724
      STAG; STAG domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials