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    hmt2 sulfide-quinone oxidoreductase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540326, updated on 22-Jun-2024

    Summary

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    Gene symbol
    hmt2
    Gene description
    sulfide-quinone oxidoreductase
    Locus tag
    SPOM_SPBC2G5.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cad1
    Old locus tag
    SPBC2G5.06c
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    Genomic context

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    See hmt2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2589004..2590933, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transketolase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-directed RNA polymerase III complex subunit Rpc25 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accumulation of metal-binding peptides in fission yeast requires hmt2+. Vande Weghe JG, et al. Mol Microbiol, 2001 Oct. PMID 11679064
    2. A fission yeast gene for mitochondrial sulfide oxidation. Vande Weghe JG, et al. J Biol Chem, 1999 May 7. PMID 10224084
    3. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    4. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
    5. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables FAD binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables FAD binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sulfide:quinone oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfide:quinone oxidoreductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular detoxification of cadmium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to cadmium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in glutathione biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phytochelatin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sulfide oxidation, using sulfide:quinone oxidoreductase IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sulfide-quinone oxidoreductase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2589004..2590933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021978.3 → NP_596067.1  sulfide-quinone oxidoreductase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596067.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13293, O94284
      Conserved Domains (1) summary
      pfam07992
      Location:29 → 357
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials