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    DNA polymerase alpha-associated DNA helicase A [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539412, updated on 18-Sep-2024

    Summary

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    Official Full Name
    DNA polymerase alpha-associated DNA helicase A
    Primary source
    PomBase:SPCC737.07c
    Locus tag
    SPOM_SPCC737.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003421.2 (1897817..1900300, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peroxin Pex28/29 Neighboring gene glutamate-cysteine ligase regulatory subunit Gcs2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene midasin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    2. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 5'-3' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables double-stranded DNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables single-stranded DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitotic DNA replication lagging strand elongation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of DNA helicase A complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nuclear replication fork IC
    Inferred by Curator
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA polymerase alpha-associated DNA helicase A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1897817..1900300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023360.3 → NP_588369.1  DNA polymerase alpha-associated DNA helicase A [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588369.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94247
      Conserved Domains (3) summary
      TIGR00376
      Location:33 → 651
      TIGR00376; DNA helicase, putative
      pfam13087
      Location:429 → 629
      AAA_12; AAA domain
      pfam13245
      Location:227 → 275
      AAA_19; Part of AAA domain
    Nucleotide Protein
    Heading Accession and Version

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