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    taf6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539133, updated on 22-Aug-2024

    Summary

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    Official Symbol
    taf6
    Primary source
    PomBase:SPCC16C4.18c
    Locus tag
    SPOM_SPCC16C4.18C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    taf50
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    Genomic context

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    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (699064..701697, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL2m Neighboring gene RNA cap binding protein cbc3 Neighboring gene protein mug123 Neighboring gene ncRNA Neighboring gene retromer complex subunit Vps5 Neighboring gene ncRNA Neighboring gene xylulose kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF. Mitsuzawa H, et al. Nucleic Acids Res, 2002 May 1. PMID 11972332, Free PMC Article
    2. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article
    3. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Helmlinger D, et al. Genes Dev, 2008 Nov 15. PMID 19056896, Free PMC Article
    4. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article
    5. TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability. Laboucarié T, et al. EMBO Rep, 2017 Dec. PMID 29079657, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TATA-binding protein-associated factor TAF6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      699064..701697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022919.3 → NP_587928.1  TATA-binding protein-associated factor TAF6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587928.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74462
      Conserved Domains (2) summary
      cd08050
      Location:9 → 363
      TAF6; TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
      COG5095
      Location:1 → 452
      TAF6; Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA) [Transcription]
    Nucleotide Protein
    Heading Accession and Version

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