U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CG30088 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246447, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG30088provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050088
    Locus tag
    Dmel_CG30088
    See related
    AllianceGenome:FB:FBgn0050088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8215; Dmel\CG30088; SP219; SP41
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG30088 in Genome Data Viewer
    Location:
    52C1-52C1; 2-75 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15691113..15692216)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11578618..11579721)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Importin beta11 Neighboring gene Centrosomal protein 89kDa Neighboring gene antisense RNA:CR44372 Neighboring gene Endoplasmic reticulum stress-associated serine protease Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes. Touré H, et al. PLoS Pathog, 2023 Mar. PMID 36972320, Free PMC Article
    2. Drosophila activating transcription factor-2 is involved in stress response via activation by p38, but not c-Jun NH(2)-terminal kinase. Sano Y, et al. Mol Biol Cell, 2005 Jun. PMID 15788564, Free PMC Article
    3. Single-cell RNA sequencing identifies novel cell types in Drosophila blood. Fu Y, et al. J Genet Genomics, 2020 Apr 20. PMID 32487456, Free PMC Article
    4. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. De Gregorio E, et al. Proc Natl Acad Sci U S A, 2001 Oct 23. PMID 11606746, Free PMC Article
    5. Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Ponting CP, et al. Genome Res, 2001 Dec. PMID 11731489

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG30088-PB
    NP_725488.3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15691113..15692216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166113.6 → NP_725488.3  uncharacterized protein Dmel_CG30088 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725488.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZA38, E0R968
      Conserved Domains (2) summary
      smart00020
      Location:44 → 272
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:45 → 273
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZA38 A1ZA38

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools